Omega-3 Fatty Acid Supplementation on Post-Exercise Inflammation, Muscle Damage, Oxidative Response, and Sports Performance in Physically Healthy Adults—A Systematic Review of Randomized Controlled Trials | Semantic Scholar (2024)

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@article{FernndezLzaro2024Omega3FA, title={Omega-3 Fatty Acid Supplementation on Post-Exercise Inflammation, Muscle Damage, Oxidative Response, and Sports Performance in Physically Healthy Adults—A Systematic Review of Randomized Controlled Trials}, author={Diego Fern{\'a}ndez-L{\'a}zaro and Soledad Arribalzaga and Eduardo Guti{\'e}rrez-Abej{\'o}n and Mohammad Ali Azarbayjani and Juan Mielgo-Ayuso and Enrique Roche}, journal={Nutrients}, year={2024}, url={https://api.semanticscholar.org/CorpusID:270804445}}
  • Diego Fernández-Lázaro, Soledad Arribalzaga, Enrique Roche
  • Published in Nutrients 27 June 2024
  • Medicine

The consumption of n-3 PUFAs improved some indicators of oxidative stress such as reduced glutathione (GSH)/oxidized glutathione (GSSG) ratio, and these may benefit the post-exercise inflammatory response, mitigate muscle damage, and decrease oxidative stress caused by exercise.

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The data indicate chronic RET reversed aging-induced loss of muscle strength and improved RMR, while FO administration combined with RET appears to enhance fat metabolism and mildly reduce some indicators of systemic inflammation.

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Fish oil (DHA+EPA) supplementation did not mitigate the adverse effects of RSHI, as measured by NfL levels; however, participants with the highest plasma DHA+ EPA concentrations tended to have lower NfF levels, emphasize the need for effective strategies to protect American football participants from the effects ofRSHI.

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Acute administration of antioxidants immediately before or during an exercise session can have beneficial effects, such as delay of fatigue and a reduction in the recovery period.

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