The current issue of JAMA (2024)

Table of Contents
Journals Podcasts Audio Highlights Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial Association Between Cost Sharing and Naloxone Prescription Dispensing Mortality and Morbidity in Adults With Rheumatic Heart Disease Trends in Naloxone Dispensing From Retail Pharmacies in the US Trends in Preeclampsia Risk Factors in the US From 2010 to 2021 The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided Early Pregnancy Loss in an Era of “Wrongful Embryonic Death” Upholding Standards for Qualified Bilingual Staff Why Should the FDA Focus on Pragmatic Clinical Research? The Weight of a Differential Anesthesia Dose and Delirium—A Picture Coming Into Focus Costs and Essential Drug Access—The Case of Naloxone Management of Depression in Adults: A Review Test-Negative Study Designs for Evaluating Vaccine Effectiveness Integrating Clinical Trials and Practice: A New JAMA Series and Call for Papers Poetry and Seeing the Sacred in Medicine Syphilis Has Surged for Reasons That Go Beyond the Pathogen That Causes It AAP Changes Its Breastfeeding Policy for People With HIV in US Counting Minutes, Steps Linked With Similar Mortality Reduction Rare Inherited Tumor Syndrome Tied to Nail Condition Progestogen May Lower Risk for More Surgery for Endometriosis Pain Having Peers With Mental Disorders Might Increase Classmates’ Risk Fish Oil Pills Associated With Increased Risk of Heart Problems in Healthy People Cognitive Impairment Underestimated Among American Indian People Early Therapy for Symptomatic COPD, Asthma Improved Quality of Life Review Calls for Standardized Long COVID Definition Radiance The Conquest of Yellow Fever What Is Lynch Syndrome? Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon—Reply Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications—Reply Errors in Table 2 Removal of Conflict of Interest Disclosure JAMA New Online Latest from the USPSTF References

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    Audio Highlights

    Abstract Full Text

    free access online only has audio

    JAMA. 2024;332(2):e2318339. doi:10.1001/jama.2023.18339

    • Audio: EEG-Guided Anesthesia and Delirium, Integrating Clinical Trials With Clinical Practice, Depression Review, and more

    Original Investigation

    Electroencephalography-Guided Anesthesia and Delirium in Older Adults After Cardiac Surgery: The ENGAGES-Canada Randomized Clinical Trial

    AlainDeschamps,MD, PhD; ArbiBen Abdallah,PhD; EricJacobsohn,MD, ChB; et al.

    Abstract Full Text

    JAMA. 2024;332(2):112-123. doi:10.1001/jama.2024.8144

    This randomized clinical trial examines whether electroencephalogram -guided anesthesia decreases the incidence of delirium after cardiac surgery among adults 60 years or older.

    • Editorial

      Anesthesia Dose and Delirium—A Picture Coming Into Focus

      MilesBerger,MD, PhD; Mark D.Neuman,MD, MSc

      JAMA

    Association Between Cost Sharing and Naloxone Prescription Dispensing

    Kao-PingChua,MD, PhD; Rena M.Conti,PhD; PoojaLagisetty,MD; et al.

    Abstract Full Text

    JAMA. 2024;332(2):124-132. doi:10.1001/jama.2024.8378

    This study evaluates the association between cost sharing and naloxone prescription abandonment (nondispensing of naloxone prescriptions) in commercial insurance and Medicare plans.

    • Editorial

      Costs and Essential Drug Access—The Case of Naloxone

      LeoBeletsky,JD, MPH; Max Jordan NguemeniTiako,MD, MS

      JAMA

    Mortality and Morbidity in Adults With Rheumatic Heart Disease

    GanesanKarthikeyan,DM; MpikoNtsekhe,PhD; ShofiqulIslam,PhD; et al.

    Abstract Full Text

    has active quiz

    JAMA. 2024;332(2):133-140. doi:10.1001/jama.2024.8258

    This prospective observational study investigates mortality rates and predictive risk factors for rheumatic heart disease in 24 endemic low- and middle-income countries and evaluates interventions like corrective valve surgery and valvuloplasty.

    • Editorial

      Rheumatic Heart Disease—A Neglected Tragedy in Young Patients

      KumarNarayanan,MD; EloiMarijon,MD, PhD

      JAMA Cardiol

    Research Letter

    Trends in Naloxone Dispensing From Retail Pharmacies in the US

    S. MichaelaRikard,PhD; Andrea E.Strahan,PhD; Lyna Z.Schieber,MD, DPhil; et al.

    Abstract Full Text

    JAMA. 2024;332(2):165-167. doi:10.1001/jama.2024.8323

    This cross-sectional study examines trends in naloxone dispensing by US retail pharmacies from 2019 to 2023, including prescriber specialty and product brand.

    Trends in Preeclampsia Risk Factors in the US From 2010 to 2021

    Mariam K.Ayyash,MD, MSCR; RodneyMcLarenJr,MD; MajidShaman,MD; et al.

    Abstract Full Text

    JAMA. 2024;332(2):167-169. doi:10.1001/jama.2024.8931

    This population-based retrospective study uses data from the National Vital Statistics System to evaluate trends in risk factors for preeclampsia in the US between 2010 and 2021.

    Special Communication

    Integrating Clinical Trials and Practice

    The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided

    Derek C.Angus,MD, MPH; Alison J.Huang,MD, MAS; Roger J.Lewis,MD, PhD; et al.

    Abstract Full Text

    has active quiz has audio

    JAMA. 2024;332(2):153-162. doi:10.1001/jama.2024.4088

    This Special Communication discusses the need for better integration of clinical trials and health care delivery enterprises.

    • Audio: Integrating Clinical Trials With the Practice of Medicine

    Viewpoint

    Health and the 2024 US Election

    Early Pregnancy Loss in an Era of “Wrongful Embryonic Death”

    Allen J.Wilcox,MD, PhD; Lisa C.Ikemoto,JD, LLM

    Abstract Full Text

    JAMA. 2024;332(2):99-100. doi:10.1001/jama.2024.7403

    This Viewpoint examines the possible legal consequences of pregnancy loss following the Alabama Supreme Court’s decision to extend personhood to laboratory-conceived embryos.

    Upholding Standards for Qualified Bilingual Staff

    AdaugoAmobi,MD, MPH

    Abstract Full Text

    JAMA. 2024;332(2):101-102. doi:10.1001/jama.2024.8896

    This Viewpoint discusses ways to ensure the proficiency of bilingual communication among health care staff in patient-clinician encounters, such as language testing and use of professional interpreters.

    Integrating Clinical Trials and Practice

    Why Should the FDA Focus on Pragmatic Clinical Research?

    Ali B.Abbasi,MD; Lesley H.Curtis,PhD; Robert M.Califf,MD

    Abstract Full Text

    JAMA. 2024;332(2):103-104. doi:10.1001/jama.2024.6227

    This Viewpoint from the FDA discusses how pragmatic clinical research—assessment that uses real-world data, often in combination with research data, after initial marketing approval—can help in evaluation of new technologies, benefit research sites in underresourced settings, and better inform regulatory decisions and clinical practice.

    • Editor's Note

      Integrating Clinical Trials and Practice: A New JAMA Series and Call for Papers

      GregoryCurfman,MD

      JAMA

    A Piece of My Mind

    The Weight of a Differential

    Maren E.Olson,MD, MPH, MEd

    Abstract Full Text

    JAMA. 2024;332(2):105-106. doi:10.1001/jama.2024.8766

    In this narrative medicine essay, when a physician’s mother begins experiencing postmenopausal bleeding, the author wonders what it would be like to hear someone’s signs and symptoms and not automatically begin to build a differential.

    Editorial

    Anesthesia Dose and Delirium—A Picture Coming Into Focus

    MilesBerger,MD, PhD; Mark D.Neuman,MD, MSc

    Abstract Full Text

    JAMA. 2024;332(2):107-108. doi:10.1001/jama.2023.26819

    Costs and Essential Drug Access—The Case of Naloxone

    LeoBeletsky,JD, MPH; Max Jordan NguemeniTiako,MD, MS

    Abstract Full Text

    JAMA. 2024;332(2):109-110. doi:10.1001/jama.2024.7012

    Review

    Management of Depression in Adults: A Review

    Gregory E.Simon,MD, MPH; NathalieMoise,MD, MS; David C.Mohr,PhD

    Abstract Full Text

    has active quiz has audio

    JAMA. 2024;332(2):141-152. doi:10.1001/jama.2024.5756

    This narrative review uses data from network meta-analyses and systematic reviews to explore the prevalence, diagnosis, and treatment of major depression in US adults, including specific forms of psychotherapy and more than 20 antidepressant medications.

    • Audio: Managing Depression in Adults

    JAMA Guide to Statistics and Methods

    Test-Negative Study Designs for Evaluating Vaccine Effectiveness

    NatalieDean,PhD; Avnika B.Amin,PhD

    Abstract Full Text

    has active quiz

    JAMA. 2024;332(2):163-164. doi:10.1001/jama.2024.5633

    This JAMA Guide to Statistics and Methods article explains the test-negative study design, an observational study design routinely used to estimate vaccine effectiveness, and examines its use in a study that estimated the performance of messenger RNA boosters against the Omicron variant.

    Editor's Note

    Integrating Clinical Trials and Practice

    Integrating Clinical Trials and Practice: A New JAMA Series and Call for Papers

    GregoryCurfman,MD

    Abstract Full Text

    free access

    JAMA. 2024;332(2):111. doi:10.1001/jama.2024.10266

    Poetry and Seeing the Sacred in Medicine

    RafaelCampo,MD, MA

    Abstract Full Text

    JAMA. 2024;332(2):174. doi:10.1001/jama.2024.7221

    Medical News & Perspectives

    Syphilis Has Surged for Reasons That Go Beyond the Pathogen That Causes It

    RitaRubin,MA

    Abstract Full Text

    has audio

    JAMA. 2024;332(2):92-95. doi:10.1001/jama.2024.2978

    This Medical News story discusses the multiple factors contributing to the resurgence of syphilis in the US.

    • Audio: June 2024 Medical News Summary

    Medical News in Brief

    AAP Changes Its Breastfeeding Policy for People With HIV in US

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10335

    Counting Minutes, Steps Linked With Similar Mortality Reduction

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10336

    • Editor's Note

      Tracking Physical Activity One Step at a Time

      Cary P.Gross,MD; Raegan W.Durant,MD, MPH

      JAMA Intern Med

    Rare Inherited Tumor Syndrome Tied to Nail Condition

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10337

    Progestogen May Lower Risk for More Surgery for Endometriosis Pain

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):96. doi:10.1001/jama.2024.10338

    Having Peers With Mental Disorders Might Increase Classmates’ Risk

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):96-97. doi:10.1001/jama.2024.10339

    Fish Oil Pills Associated With Increased Risk of Heart Problems in Healthy People

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10340

    Cognitive Impairment Underestimated Among American Indian People

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10341

    Early Therapy for Symptomatic COPD, Asthma Improved Quality of Life

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10342

    Review Calls for Standardized Long COVID Definition

    EmilyHarris

    Abstract Full Text

    JAMA. 2024;332(2):97. doi:10.1001/jama.2024.10343

    Poetry and Medicine

    Radiance

    RonnieSirmans,ABJ

    Abstract Full Text

    JAMA. 2024;332(2):174. doi:10.1001/jama.2024.7205

    • Editor's Note

      Poetry and Seeing the Sacred in Medicine

      RafaelCampo,MD, MA

      JAMA

    JAMA Revisited

    The Conquest of Yellow Fever

    Abstract Full Text

    JAMA. 2024;332(2):175. doi:10.1001/jama.2023.18340

    JAMA Patient Page

    What Is Lynch Syndrome?

    KaseyHornbuckle,MD; Cassandra D. L.Fritz,MD, MPHS

    Abstract Full Text

    free access

    JAMA. 2024;332(2):178. doi:10.1001/jama.2024.8552

    This JAMA Patient Page describes Lynch syndrome, its risk factors and diagnosis, and its association with colorectal cancer and other specific cancers.

    Comment & Response

    Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon

    AllisonKratka,MD; Rita F.Redberg,MD, MSc

    Abstract Full Text

    JAMA. 2024;332(2):169. doi:10.1001/jama.2024.9520

    Coronary In-Stent Restenosis Treated With Pacl*taxel-Coated Balloon vs Uncoated Balloon—Reply

    Robert W.Yeh,MD, MSc; Ajay J.Kirtane,MD, SM; AGENT IDE Investigators

    Abstract Full Text

    JAMA. 2024;332(2):169-170. doi:10.1001/jama.2024.9523

    Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications

    David A.Milder,BMedMD, BSc; Tamara Y.Milder,MBBS, MMed; PeterKam,MBBS, MD

    Abstract Full Text

    JAMA. 2024;332(2):170-171. doi:10.1001/jama.2024.10029

    Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications

    MarcLevi,MD

    Abstract Full Text

    JAMA. 2024;332(2):171. doi:10.1001/jama.2024.10023

    Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications

    Ion A.Hobai,MD, PhD

    Abstract Full Text

    JAMA. 2024;332(2):171-172. doi:10.1001/jama.2024.10026

    Preoperative GLP-1 Receptor Agonists and Risk of Postoperative Respiratory Complications—Reply

    Anjali A.Dixit,MD, MPH; Brian T.Bateman,MD, MS; Eric C.Sun,MD, PhD

    Abstract Full Text

    JAMA. 2024;332(2):172-173. doi:10.1001/jama.2024.10032

    Correction

    Errors in Table 2

    Abstract Full Text

    free access

    JAMA. 2024;332(2):173. doi:10.1001/jama.2024.11152

    Removal of Conflict of Interest Disclosure

    Abstract Full Text

    free access

    JAMA. 2024;332(2):173. doi:10.1001/jama.2024.11869

    JAMA Masthead

    JAMA

    Abstract Full Text

    free access

    JAMA. 2024;332(2):89-90. doi:10.1001/jama.2023.18338

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    Acceptability of Hospital-at-Home Care and Capacity for Caregiver Burden

    Research Letter | July 8, 2024

    The Tobacco Industry Has No Business Funding Continuing Medical Education

    Viewpoint | July 8, 2024

    Essential Tremor

    JAMA Insights | July 8, 2024

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